Fig 1: Catalase and superoxide dismutase dictate the survival of irradiated HIV-1-infected cells. (A) Chronically HIV-1-infected T-cell line ACH2 and pro-monocytes U1, and corresponding uninfected CEM and U937, treated with 10 Gy of ionizing radiation (IR), lysed (5 days post-IR) and probed for catalase (CAT) and superoxide dismutase (SOD) via Western blot. (B) Densitometry analysis of the CAT and SOD bands was performed. (C) Two dosages of exogenous CAT (3.08 U) and SOD (16.82 U) were added to U1 and ACH2 cells in two dosages to over the time period of 5 days (Day 1 and 3) to test for cell viability recovery after IR treatment.